Multiple Sclerosis & Related Disorders: A Comprehensive Review 2025

Saturday, October 25, 2025, 7:30 AM - 5:35 PM, Margaritaville Hollywood Beach Hotel, Hollywood, FL


AMA PRA Category 1 Credits™ (7.75 hours), Non-Physician Attendance (7.75 hours)

This course will provide an updated overview of emerging concepts in multiple sclerosis (MS) and related immune-mediated disorders of the central nervous system (CNS). Novel therapies for MS continue to be developed, each with unique mechanisms of action. While significant progress has been made in reducing relapse rates, progressive forms of the disease remain a major area of unmet need. The course will explore recent advancements in managing progressive MS, including detailed discussions of successful Phase 3 clinical trials

The program will include real-world case studies highlighting challenging diagnostic and therapeutic scenarios. Interactive sessions, including case presentations, faculty-led discussions, panel debates, and Q&A segments, will provide opportunities for direct engagement and knowledge exchange between faculty and attendees.

1. Assess the MRI criteria and spinal fluid for diagnosis of MS using the most appropriate and current sequences
2. Evaluate the new criteria and how to use the paraclinical testing which includes magnetic resonance imaging and spinal fluid analysis
3. Examine the advances made in cell-based therapies which include CAR-T cells and stem cell therapies
4. Examine the current status of disease-modifying therapies in MS
5. Apply the international criteria for diagnosis of multiple sclerosis to facilitate early and appropriate diagnosis to institute disease-modifying therapies early and appropriately
6. Diagnose MS appropriate and institute treatment early to minimize long-term disability using the current criteria
7. Develop a clinical plan to identify and diagnose early features suggestive of Neuromyelitis Optica Spectrum Disorders (NMOSD) based on knowledge of the current diagnostic criteria and how these differ from criteria to diagnose MS or other CNS autoimmune disorders
8. Consider neuroimmunologic mechanisms of action, the pathogenetic role of complement, and evidence for efficacy to assess the risk versus benefit of available and pending disease modifying therapy (DMT) for NMOSD
9. Recognize and differentiate between the clinical presentations of optic neuritis that are more likely to involve anti-MOG antibodies compared to other causes, such as neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis
10. Distinguish the key clinical features that differentiate NMOSD from MOGAD, with a particular focus on the characteristic manifestations and diagnostic criteria of each disorder
11. Appropriately diagnosis and distinguish MS from NMOSD in patients considering family planning
12. Assess the mechanisms underlying complications of checkpoint therapies decide which antibodies to examine for specific encephalitis

For more information and registration click here.

 

The University of Miami Leonard M. Miller School of Medicine designates this Live Activity for a maximum of 7.75 of AMA PRA Category 1 Credits^TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Cancellation Policy

Refunds will be made only if written notice of cancellation is received prior to September 25, 2025.

University of Miami Healthcare System reserves the right to cancel or postpone this program if necessary; in the event of cancellation, course fees will be fully refunded. We are not responsible for other costs incurred such as non-refundable airline tickets or hotel penalties. Please contact the CME Conference Coordinator Vanesa Clark at [email protected]

Accessibility Statement
 
University of Miami Healthcare System is committed to ensuring that its programs, services, goods and facilities are accessible to individuals with disabilities as specified under Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Amendments Act of 2008.  If you have needs that require special accommodations, including dietary concerns, please contact the CME Conference Coordinator Vanesa Clark at [email protected]

Mitigation of Relevant Financial Relationships

The University of Miami adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Saturday, October 25, 2025